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Introduction: A Crisis Hiding in Plain Sight Among the nearly 200 million people worldwide with hyperuricemia (high uric acid), a silent crisis is unfolding. While public attention is fixated on gout—the painful, inflammatory arthritis caused by high uric acid—a significant threat to liver health is often overlooked. Hyperuricemia is not just an enemy to your […]

Introduction: An Uncontrolled Global Epidemic Nearly 200 million people worldwide suffer from hyperuricemia, and the vast majority are silently progressing towards gout. A study in The Lancet projects that the global number of gout patients will approach 60 million by 2025. Yet, a staggering reality persists: only about 22% of gout patients manage to keep their uric acid levels

Introduction. Gout is a painful form of inflammatory arthritis caused by elevated blood uric acid that leads to sharp urate crystal deposits in jointsmy.clevelandclinic.orgmy.clevelandclinic.org. These crystals trigger intense swelling, redness and pain (often in the big toe) during sudden flaresmy.clevelandclinic.org. Standard gout management focuses on lowering uric acid (e.g. with xanthine oxidase inhibitors or uricosurics)

IntroductionUrate-lowering drugs are a cornerstone of treatment for hyperuricemia and gout. The primary medications include xanthine oxidase inhibitors like allopurinol and febuxostat, which reduce uric acid production, and uricosuric agents like benzbromarone, which promote its excretion. While essential for managing gout, the long-term use of these drugs is associated with potential and scientifically documented risks

IntroductionDo you constantly feel tired and drained? Suffer from itchy, sensitive skin? Experience dizziness, dry eyes, or even nausea and bloating? These seemingly unrelated symptoms can all point to one underlying issue: chronic inflammation. The root of this inflammation is often found in the health of your liver and gallbladder system. As the body’s master

Introduction: The True Source of Gout Pain For anyone who has experienced gout, the first word that comes to mind is pain. But the true source of this agony is often the silent formation of what are known as “tophi” in your hands, feet, and other joints. Gout tophi are the direct result of long-term, uncontrolled

IntroductionChronic fatigue is a pervasive complaint, often attributed to stress or burnout. However, one of the most overlooked causes of persistent exhaustion is a struggling liver. As the body’s central power station and primary filter, the liver’s health is directly tied to your daily energy. When its function declines, it can trigger a systemic energy

IntroductionWhen struggling with brain fog, irritability, or persistent mood swings, we often look to psychological stress or neurological issues as the primary culprits. However, an increasing body of clinical evidence suggests that our emotional and cognitive states are profoundly linked to the health of our liver. Chronic Liver Disease (CLD) can disrupt central nervous system

IntroductionExperiencing persistent low mood or increased irritability is often primarily attributed to psychological factors. However, emerging clinical research indicates that these sudden emotional shifts could, in fact, be physiological manifestations of declining kidney function. Chronic Kidney Disease (CKD) impacts central nervous system function through several well-defined pathophysiological pathways.I. Physiological Mechanisms: The Kidney-Brain Connection Neurotoxicity of

FunctionIntroductionIn today’s world, maintaining stable blood sugar has become one of our toughest health challenges. According to the International Diabetes Federation, an estimated 537 million adults globally are living with diabetes, with several times that number in a state of prediabetes. This persistent state of blood sugar imbalance can cause irreversible damage to our most